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(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-二甲基-2-((S)-3-甲基-2-(甲胺基)丁酰胺基)丁酰胺基)-3-甲氧基-5-甲基庚酰)吡咯烷-2-基)-3-甲氧基-2-甲基丙酰胺基)-3-苯基丙酸,98+%
CAS号：745017-94-1 分子式：C39H65N5O8
MDL：
详情介绍
化合物简介
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody.
基本信息
CAS：745017-94-1
中文别名：一甲基澳瑞他汀 F;
英文别名：MMAF;Monomethylauristatin F;Monomethyl auristatin phenylalanine;(2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;
分子式：C39H65N5O8
分子量：731.962
精确质量：731.483
Psa：166.61
中文别名：一甲基澳瑞他汀 F;
英文别名：MMAF;Monomethylauristatin F;Monomethyl auristatin phenylalanine;(2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;
分子式：C39H65N5O8
分子量：731.962
精确质量：731.483
Psa：166.61
Logp：4.2142
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